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CLASSIFICATION OF MUCOLYTICS & EXPECTORANTS

CLASSIFICATION OF MUCOLYTICS & EXPECTORANTS

 

CLASSIFICATION OF EXPECTORANTS

A) CHEMICAL CLASSIFICATION OF EXPECTORANTS:

Alkaloids = Ipecacuanha

Guasea rasbyi = Cocillana.

Glycosidal saponins = Senega, Squill.

Iodides = Sodium iodide, Potassium iodide.

B) PHARMACOLOGICAL CLASSIFICATION OF EXPECTORANTS :

i) DRUGS ACTING REFLEXLY :

Ipecacuanha, Ammonium chloride, Ammonium

bicarbonate, Guaifenesin, Cocillana, Senega,

Squill, Terpen hydrate.

ii) DRUGS ACTING DIRECTLY :

Sodium iodide and Potassium iodide.

C) THERAPEUTIC CLASSIFICATION OF EXPECTORANTS:

i) Irritant to Gastric mucosa :

Ipecacuanha, Squill, Senega, Ammonium

Chloride and Ammonium bicarbonate.

ii) Carminative use : Ammonium bicarbonate

iii) Decrease viscosity of sputum :

Guaifenesin, Sodium and Potassium iodide.

iv) Chronic bronchitis and TB: Sodium iodide.

 

 

CLASSIFICATION OF MUCOLYTICS

A) CHEMICAL CLASSIFICATION OF MUCOLYTICS:

Alkaloid derivative: Bromhexine.

Amino acid derivative: Carbocisteine.

B) PHARMACOLOGICAL CLASSIFICATION OF MUCOLYTICS:

i) Inhalational Mucolytics :

Acetylcysteine, Tyloxapol.

ii) Oral Mucolytics :

Acetylcysteine, Bromhexine, Carbocisteine,

Methylcysteine.

C) THERAPEUTIC CLASSIFICATION OF MUCOLYTICS:

i) Chronic bronchitis :

Carbocisteine, Bromhexine.

ii) Bronchial asthma :

Tyloxapol, Bromhexine

iii)Mucoviscidosis:Bromhexine, Acetylcysteine,

methylcysteine.